Histopathologic and ultrastructural findings of photocoagulation lesions produced by transpupillary diode laser in the rabbit retina.

نویسندگان

  • H. K. Cho
  • Y. W. Park
  • Y. J. Kim
  • K. H. Shyn
چکیده

Transpupillary retinal photocoagulations were performed on ten eyes of five pigmented rabbits using a diode laser (Nidek Co., LTD, Aichi, Japan) emitting infrared radiation at 800 nm wavelength. A histological and an ultrastructural study on the treated eyes were done at 1, 3, 5, and 7 days after retinal photocoagulations. The purpose of this study was to observe the sequential changes in the retina and the choroid following transpupillary diode laser retinal photocoagulations at the parameters of laser power which produced a grayish white retinal discoloration with distinct white center. It seemed that the lesion was grade 3 retinal photocoagulation by Tso et al's classification. It appeared that the parameters necessary to produce grade 3 photocoagulation lesions were 160 mW power, and 0.2 second duration at 200 microns size. In general, with an agreement to other reports, histologic study of the diode laser lesions showed that the outer retina was damaged more severely than the inner retina. However, on day 1 after laser treatment, the alterations were more profound in the inner retina than in the outer retina and an occasional swelling of the axons in the nerve fiber layer was observed on the ultrastructural study. The results observed have not been found in other previous studies and suggest that the inner retina might be injured directly by 800 nm wavelength diode laser radiations. Thus we could conclude that 800 nm wavelength diode radiation might be absorbed by melanin pigment and also by other chromophores contained in inner retinal tissues. Further studies must follow to verify the laser-tissue interactions in diode laser retinal photocoagulations.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Transpupillary Diode Laser Retinal Photocoagulation for the Treatment of Retinopathy of Prematurity: Experience in Southern Iran

متن کامل

Transscleral Photocoagulation to Treat ROP in Eyes with Media Opacity

It has been well established that laser treatment for type 1 prethreshold retinopathy of prematurity is effective in approximately 90 percent of treated eyes, avoiding retinal detachment.1 Transpupillary laser therapy is certainly the standard; however, there are circumstances in which transpupillary treatment may be difficult or impossible to perform thus allowing progression of retinopathy of...

متن کامل

[Transscleral infrared laser retinal photocoagulation experimental study under low visibility conditions].

PURPOSE Retinal photocoagulation under poor visualization condition is often required. Transscleral infrared laser can be used as an alternative to regular transpupillary treatment. Based upon retinographic measurements, we proposed to estimate the reproducibility as well as ocular wall permeability rate for this treatment. Our primary goal was to evaluate whether this technique can deliver ade...

متن کامل

RETINOPATHY of PREMATURITY Transscleral Retinal Photocoagulation (TSRPC) Retinopathy of Prematurity Transscleral Retinal Photocoagulation (TSRPC)

Retinopathy of Prematurity Transscleral Retinal Photocoagulation (TSRPC) The 810 nm diode laser wavelength makes lens-sparing transscleral coagulation of the retina possible, and to evaluate the efficacy and safety of transscleral diode laser coagulation for threshold ROP, the authors performed a controlled clinical study. Forty eyes of 20 preterm infants (gestational age 24-29 weeks, mean 26.8...

متن کامل

Effects of Laser Physical Parameters on Lesion Size in Retinal Photocoagulation Surgery: Clinical OCT and Experimental Study

Introduction: The aim of the present study was to determine burn intensity in retinal laser photocoagulation based on laser parameters; wavelength, power, beam size and pulse duration, using Optical Coherence Tomography (OCT), fundus camera, physical eye model and computer simulation in a clinical study.Materials and Methods: Participants were 10 adult patients between 50-80 years with prolifer...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of Korean Medical Science

دوره 8  شماره 

صفحات  -

تاریخ انتشار 1993